CRTAM Antikörper (AA 260-340)

Produktnummer ABIN7228068

Der Kaninchen Polyklonal anti-CRTAM Antikörper (ABIN7228068) detektiert spezifisch CRTAM in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für CRTAM Antikörper (AA 260-340) (ABIN7228068)

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRTAM Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-CRTAM Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: Rabbit Anti-CRTAM Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CRTAM protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CRTAM protein at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Andere Bezeichnung: CRTAM

Hintergrund: Class-I MHC-restricted T-cell-associated molecule, CD_antigen: CD355CRTAM (Cytotoxic And Regulatory T-Cell Molecule) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. GO annotations related to this gene include receptor binding. An important paralog of this gene is CADM1. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Molekulargewicht: 43kD

Gen-ID: 56253

UniProt: O95727

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation