CRLF1 Antikörper (AA 50-130)

Produktnummer ABIN7228058

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CRLF1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für CRLF1 Antikörper (AA 50-130) (ABIN7228058)

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRLF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CRLF1 Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Rabbit Anti-CRLF1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CRLF1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CRLF1 protein at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CRLF1

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Andere Bezeichnung: CRLF1

Hintergrund: Cytokine receptor-like factor 1, Cytokine-like factor 1, ZcytoR5CRLF1 (Cytokine Receptor Like Factor 1) is a Protein Coding gene. Diseases associated with CRLF1 include Cold-Induced Sweating Syndrome 1 and Crlf1-Related Cold-Induced Sweating Syndrome Including Crisponi Syndrome. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in CRLF1 result in Crisponi syndrome and cold-induced sweating syndrome.

Molekulargewicht: 46kD

Gen-ID: 9244

UniProt: O75462