CYB5R3 Antikörper (AA 110-190)

Produktnummer ABIN7214388

Der Kaninchen-Polyklonal Anti-CYB5R3-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet zum Nachweis von CYB5R3 in Proben aus Human. }

Kurzübersicht für CYB5R3 Antikörper (AA 110-190) (ABIN7214388)

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYB5R3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CYB5R3 Antikörper

Bindungsspezifität: AA 110-190

Verwendungszweck: CYB5R3 Polyclonal Antibody

Spezifität: CYB5R3 Polyclonal Antibody detects endogenous levels of CYB5R3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CYB5R3 at AA range: 110-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CYB5R3

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Andere Bezeichnung: CYB5R3

Hintergrund: Rabbit Anti-CYB5R3 Polyclonal Antibody,CYB5R3, DIA1, NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1,CYB5R3 encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in CYB5R3 cause methemoglobinemias.,NADH-cytochrome b5 reductase 3

Molekulargewicht: observerd band 34kDa

Gen-ID: 1727

UniProt: P00387

Pathways: SARS-CoV-2 Protein Interaktom