CysLTR1 Antikörper (AA 100-180)

Produktnummer ABIN7214460

Der Kaninchen Polyklonal anti-CysLTR1 Antikörper (ABIN7214460) detektiert spezifisch CysLTR1 in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CysLTR1 Antikörper (AA 100-180) (ABIN7214460)

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CysLTR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-CysLTR1 Antikörper

Bindungsspezifität: AA 100-180

Verwendungszweck: Rabbit Anti-CysLTR1 Polyclonal Antibody

Spezifität: CysLTR1 Polyclonal Antibody detects endogenous levels of CysLTR1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CysLTR1 at AA range: 100-180

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CysLTR1

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Andere Bezeichnung: CysLTR1

Hintergrund: CYSLTR1, CYSLT1, Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81CYSLTR1 encodes a member of the G-protein coupled receptor 1 family. Cysteinyl leukotriene receptor 1 is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of CYSLTR1 is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 38kD

Gen-ID: 10800

UniProt: Q9Y271