Cyclin T2 Antikörper (AA 510-590)

Produktnummer ABIN7227668

Der Kaninchen Polyklonal anti-Cyclin T2 Antikörper wird verwendet zum Nachweis von Cyclin T2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Cyclin T2 Antikörper (AA 510-590) (ABIN7227668)

Target: Cyclin T2 (CCNT2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin T2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cyclin T2 Antikörper

Bindungsspezifität: AA 510-590

Verwendungszweck: Rabbit Anti-CCNT2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CCNT2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCNT2 protein at AA range: 510-590

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cyclin T2

Target: Cyclin T2 (CCNT2)

Andere Bezeichnung: CCNT2

Hintergrund: Cyclin-T2, CycT2The protein encoded by CCNT2 (Cyclin T2) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 80kD

Gen-ID: 905

UniProt: O60583