Cullin 7 Antikörper (AA 1570-1650)

Produktnummer ABIN7228102

Der Kaninchen Polyklonal anti-Cullin 7 Antikörper wird verwendet zum Nachweis von Cullin 7 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Cullin 7 Antikörper (AA 1570-1650) (ABIN7228102)

Target: Cullin 7 (CUL7)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cullin 7 Antikörper

Bindungsspezifität: AA 1570-1650

Verwendungszweck: Rabbit Anti-CUL7 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CUL7 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CUL7 protein at AA range: 1570-1650

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cullin 7

Target: Cullin 7 (CUL7)

Andere Bezeichnung: CUL7

Hintergrund: Cullin-7, CUL-7The protein encoded by CUL7 (Cullin 7) is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in CUL7 are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for CUL7. CUL7 is a Protein Coding gene. Diseases associated with CUL7 include 3-M Syndrome 1 and 3-M Syndrome, Cul7-Related. Among its related pathways are Class I MHC mediated antigen processing and presentation and Unfolded Protein Response (UPR).

Molekulargewicht: 186kD

Gen-ID: 9820

UniProt: Q14999

Pathways: ER-Nucleus Signaling