Cullin 7 Antikörper (AA 1570-1650)

Produktnummer ABIN7228102

Der Kaninchen Polyklonal Anti-Cullin 7 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Cullin 7 in Proben von Human und Maus zu detektieren.

Kurzübersicht für Cullin 7 Antikörper (AA 1570-1650) (ABIN7228102)

Target: Cullin 7 (CUL7)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cullin 7 Antikörper

Bindungsspezifität: AA 1570-1650

Verwendungszweck: CUL7 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CUL7 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CUL7 protein at AA range: 1570-1650

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Cullin 7

Target: Cullin 7 (CUL7)

Andere Bezeichnung: CUL7

Hintergrund: Rabbit Anti-CUL7 Polyclonal Antibody,Cullin-7, CUL-7,The protein encoded by CUL7 (Cullin 7) is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in CUL7 are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for CUL7. CUL7 is a Protein Coding gene. Diseases associated with CUL7 include 3-M Syndrome 1 and 3-M Syndrome, Cul7-Related. Among its related pathways are Class I MHC mediated antigen processing and presentation and Unfolded Protein Response (UPR).,CUL7

Molekulargewicht: observerd band 186kDa

Gen-ID: 9820

UniProt: Q14999

Pathways: ER-Nucleus Signaling