COX11 Antikörper (AA 30-110)

Produktnummer ABIN7219602

Dieser Anti-COX11 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von COX11 in ELISA, WB, IF und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für COX11 Antikörper (AA 30-110) (ABIN7219602)

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX11 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-COX11 Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: COX11 Polyclonal Antibody

Spezifität: COX11 Polyclonal Antibody detects endogenous levels of COX11 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human COX11 at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu COX11

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Andere Bezeichnung: COX11

Hintergrund: Rabbit Anti-COX11 Polyclonal Antibody,COX11, Cytochrome c oxidase assembly protein COX11, mitochondrial,Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX11 encodes COX11, cytochrome c oxidase copper chaperone which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.,Cytochrome c oxidase assembly protein COX11 mitochondrial

Molekulargewicht: observerd band 31kDa

Gen-ID: 1353

UniProt: Q9Y6N1

Pathways: Regulation of Carbohydrate Metabolic Process