COX-1 Antikörper (AA 520-600)

Produktnummer ABIN7214300

Der Kaninchen Polyklonal anti-COX-1 Antikörper wird verwendet zum Nachweis von COX-1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für COX-1 Antikörper (AA 520-600) (ABIN7214300)

Target: COX-1

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-COX-1 Antikörper

Bindungsspezifität: AA 520-600

Verwendungszweck: Rabbit Anti-Cox-1 Polyclonal Antibody

Spezifität: Cox-1 Polyclonal Antibody detects endogenous levels of Cox-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Cox-1 at AA range: 520-600

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu COX-1

Target: COX-1

Hintergrund: PTGS1, COX1, Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1PTGS1 is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Prostaglandin-endoperoxide synthase 1 regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, prostaglandin-endoperoxide synthase 1 has been identified as a moonlighting protein. Prostaglandin-endoperoxide synthase 1 may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 70kD

Gen-ID: 5742

UniProt: P23219