CFHR1 Antikörper

Produktnummer ABIN7228530

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CFHR1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CFHR1 Antikörper (ABIN7228530)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CFHR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CFHR1 Antikörper

Verwendungszweck: Rabbit Anti-FHR1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FHR1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FHR1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Andere Bezeichnung: FHR1

Hintergrund: Complement factor H-related protein 1, FHR-1, H factor-like protein 1, H-factor-like 1, H36CFHR1 encodes Complement Factor H Related 1 belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Molekulargewicht: 36kD

Gen-ID: 3078

UniProt: Q03591