Cofilin Antikörper (AA 30-110)

Produktnummer ABIN7214276

Der Kaninchen Polyklonal Anti-Cofilin Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, Cofilin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Cofilin Antikörper (AA 30-110) (ABIN7214276)

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cofilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Cofilin Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: Cofilin Polyclonal Antibody

Spezifität: Cofilin Polyclonal Antibody detects endogenous levels of Cofilin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Cofilin at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Cofilin

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Andere Bezeichnung: Cofilin

Hintergrund: Rabbit Anti-Cofilin Polyclonal Antibody,CFL1, CFL, Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform, CFL2, Cofilin-2, Cofilin, muscle isoform,CFL2 encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. Cofilin 2 is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in CFL2 cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.,Cofilin-1

Molekulargewicht: observerd band 19kDa

Gen-ID: 1073, 1072

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events