Coagulation Factor IX Antikörper (AA 412-461)

Produktnummer ABIN7226924

Der Kaninchen Polyklonal anti-Coagulation Factor IX Antikörper (ABIN7226924) detektiert spezifisch Coagulation Factor IX in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Coagulation Factor IX Antikörper (AA 412-461) (ABIN7226924)

Target: Coagulation Factor IX (F9)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor IX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Coagulation Factor IX Antikörper

Bindungsspezifität: AA 412-461

Verwendungszweck: Rabbit Anti-Factor IX Polyclonal Antibody

Spezifität: Factor IX Polyclonal Antibody detects endogenous levels of Factor IX.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Factor IX at AA range: 412-461

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Coagulation Factor IX

Target: Coagulation Factor IX (F9)

Andere Bezeichnung: Factor IX

Hintergrund: Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTCF9(coagulation factor IX) encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of F9, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Molekulargewicht: 52kD

Gen-ID: 2158

UniProt: P00740