CLDN8 Antikörper (AA 50-130)

Produktnummer ABIN7225800

Dieser Anti-CLDN8 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CLDN8 in WB und ELISA. Geeignet für Human.

Kurzübersicht für CLDN8 Antikörper (AA 50-130) (ABIN7225800)

Target: CLDN8 (Claudin 8 (CLDN8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CLDN8 Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Claudin-8 Polyclonal Antibody

Spezifität: Claudin-8 Polyclonal Antibody detects endogenous levels of Claudin-8 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Claudin-8 at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CLDN8

Target: CLDN8 (Claudin 8 (CLDN8))

Andere Bezeichnung: Claudin-8

Hintergrund: Rabbit Anti-Claudin-8 Polyclonal Antibody,CLDN8, Claudin-8,CLDN8 (claudin 8) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of CLDN8 has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.,Claudin-8

Molekulargewicht: observerd band 28kDa

Gen-ID: 9073

UniProt: P56748

Pathways: Hepatitis C