Claudin 5 Antikörper

Produktnummer ABIN7224718

Der Kaninchen Polyklonal anti-Claudin 5 Antikörper wird verwendet zum Nachweis von Claudin 5 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC, ELISA und IF.

Kurzübersicht für Claudin 5 Antikörper (ABIN7224718)

Target: Claudin 5 (CLDN5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Claudin 5 Antikörper

Verwendungszweck: Rabbit Anti-Claudin-5 Polyclonal Antibody

Spezifität: Claudin-5 Polyclonal Antibody detects endogenous levels of Claudin-5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Claudin-5 around the non-phosphorylation site of Y217

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Claudin 5

Target: Claudin 5 (CLDN5)

Andere Bezeichnung: Claudin-5

Hintergrund: CLDN5, AWAL, TMVCF, Claudin-5, Transmembrane protein deleted in VCFS, TMDVCFCLDN5 (claudin 5) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in CLDN5 have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for CLDN5.

Molekulargewicht: 23kD

Gen-ID: 7122

UniProt: O00501

Pathways: Hepatitis C