Claudin 19 Antikörper (AA 50-130)

Produktnummer ABIN7214214

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Claudin 19 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für Claudin 19 Antikörper (AA 50-130) (ABIN7214214)

Target: Claudin 19 (CLDN19)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Claudin 19 Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Claudin-19 Polyclonal Antibody

Spezifität: Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Claudin-19 at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Claudin 19

Target: Claudin 19 (CLDN19)

Andere Bezeichnung: Claudin-19

Hintergrund: Rabbit Anti-Claudin-19 Polyclonal Antibody,CLDN19, Claudin-19,The product of CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in CLDN19 are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for CLDN19.,Claudin-19

Molekulargewicht: observerd band 23kDa

Gen-ID: 149461

UniProt: Q8N6F1

Pathways: Cell-Cell Junction Organization, Hepatitis C