Claudin 1 Antikörper

Produktnummer ABIN7225808

Dieser Anti-Claudin 1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Claudin 1 in WB und ELISA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für Claudin 1 Antikörper (ABIN7225808)

Target: Claudin 1 (CLDN1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Claudin 1 Antikörper

Verwendungszweck: Claudin-1 Polyclonal Antibody

Spezifität: Claudin-1 Polyclonal Antibody detects endogenous levels of Claudin-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Claudin-1 around the non-phosphorylation site of Y210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: Claudin-1

Hintergrund: Rabbit Anti-Claudin-1 Polyclonal Antibody,CLDN1, CLD1, SEMP1, Claudin-1, Senescence-associated epithelial membrane protein,Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by CLDN1 (claudin 1), a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.,Claudin-1

Molekulargewicht: observerd band 30kDa

Gen-ID: 9076

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C