Chp2 Antikörper (AA 70-150)
Kurzübersicht für Chp2 Antikörper (AA 70-150) (ABIN7214202)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 70-150
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Verwendungszweck
- CHP2 Polyclonal Antibody
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Spezifität
- CHP2 Polyclonal Antibody detects endogenous levels of CHP2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human CHP2 at AA range: 70-150
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Chp2
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Hintergrund
- Rabbit Anti-CHP2 Polyclonal Antibody,CHP2, HCA520, Calcineurin B homologous protein 2, Hepatocellular carcinoma-associated antigen 520,CHP2 product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. Calcineurin like EF-hand protein 2 shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). CHP2 was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.,Calcineurin B homologous protein 2
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Molekulargewicht
- observerd band 22kDa
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Gen-ID
- 63928
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UniProt
- O43745
Target
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