CLCN2 Antikörper

Produktnummer ABIN7227936

Der Kaninchen Polyklonal anti-CLCN2 Antikörper (ABIN7227936) detektiert spezifisch CLCN2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CLCN2 Antikörper (ABIN7227936)

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CLCN2 Antikörper

Verwendungszweck: Rabbit Anti-CLCN2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CLCN2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CLCN2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CLCN2

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Andere Bezeichnung: CLCN2

Hintergrund: Chloride channel protein 2, ClC-2CLCN2 (Chloride Voltage-Gated Channel 2) is a Protein Coding gene. Diseases associated with CLCN2 include Leukoencephalopathy With Ataxia and Epilepsy, Idiopathic Generalized 11. Among its related pathways are Hepatic ABC Transporters and Activation of cAMP-Dependent PKA. CLCN2 encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in CLCN2 may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for CLCN2.

Molekulargewicht: 98kD

Gen-ID: 1181

UniProt: P51788