CCR7 Antikörper (AA 140-220)

Produktnummer ABIN7219462

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CCR7 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human und Affe.

Kurzübersicht für CCR7 Antikörper (AA 140-220) (ABIN7219462)

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-CCR7 Antikörper

Bindungsspezifität: AA 140-220

Verwendungszweck: CKR-7 Polyclonal Antibody

Spezifität: CKR-7 Polyclonal Antibody detects endogenous levels of CKR-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CKR-7 at AA range: 140-220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CCR7

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Andere Bezeichnung: CKR-7

Hintergrund: Rabbit Anti-CKR-7 Polyclonal Antibody,CCR7, CMKBR7, EBI1, EVI1, C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD antigen CD19,The C-C motif chemokine receptor 7 encoded by CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.,C-C chemokine receptor type 7

Molekulargewicht: observerd band 43kDa

Gen-ID: 1236

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process