CBLN2 Antikörper (AA 130-210)

Produktnummer ABIN7214156

Dieser Anti-CBLN2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CBLN2 in WB und ELISA. Geeignet für Human, Ratte, Maus und Affe.

Kurzübersicht für CBLN2 Antikörper (AA 130-210) (ABIN7214156)

Target: CBLN2 (Cerebellin 2 Precursor (CBLN2))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBLN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CBLN2 Antikörper

Bindungsspezifität: AA 130-210

Verwendungszweck: Cerebellin 2 Polyclonal Antibody

Spezifität: Cerebellin 2 Polyclonal Antibody detects endogenous levels of Cerebellin 2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Cerebellin 2 at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CBLN2

Target: CBLN2 (Cerebellin 2 Precursor (CBLN2))

Andere Bezeichnung: Cerebellin 2

Hintergrund: Rabbit Anti-Cerebellin 2 Polyclonal Antibody,CBLN2, Cerebellin-2,Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other's degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.,Cerebellin-2

Molekulargewicht: observerd band 24kDa

Gen-ID: 147381

UniProt: Q8IUK8