CERKL Antikörper (AA 310-390)

Produktnummer ABIN7214160

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CERKL in ELISA, WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CERKL Antikörper (AA 310-390) (ABIN7214160)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CERKL Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CERKL Antikörper

Bindungsspezifität: AA 310-390

Verwendungszweck: Rabbit Anti-CERKL Polyclonal Antibody

Spezifität: CERKL Polyclonal Antibody detects endogenous levels of CERKL protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CERKL at AA range: 310-390

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Andere Bezeichnung: CERKL

Hintergrund: CERKL, Ceramide kinase-like proteinCERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.

Molekulargewicht: 63kD

Gen-ID: 375298

UniProt: Q49MI3