CEP55 Antikörper (AA 50-130)

Produktnummer ABIN7214148

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CEP55 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für CEP55 Antikörper (AA 50-130) (ABIN7214148)

Target: CEP55 (Centrosomal Protein 55kDa (CEP55))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP55 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CEP55 Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Rabbit Anti-CEP55 Polyclonal Antibody

Spezifität: CEP55 Polyclonal Antibody detects endogenous levels of CEP55 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CEP55 at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CEP55

Target: CEP55 (Centrosomal Protein 55kDa (CEP55))

Andere Bezeichnung: CEP55

Hintergrund: CEP55, C10orf3, URCC6, Centrosomal protein of 55 kDa, Cep55, Up-regulated in colon cancer 6CEP55 (Centrosomal protein of 55 kDa), also known as URCC6 (Up-regulated in colon cancer 6), is a 464 amino acid protein that localizes to the centrosome during interphase and may be found throughout the cell during mitosis. Widely expressed with highest expression in testis and lower expression in thymus, bone marrow, placenta, fetal heart, digestive tract and several carcinomas, CEP55 exists as a homodimer that interacts with centrosome components and is involved in mitotic exit and cytokinesis. Human CEP55 undergoes several phosphorylation events throughout the cell cycle, most of which are necessary for proper CEP55 function. Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression. Two isoforms of CEP55 are expressed due to alternative splicing events.

Molekulargewicht: 54kD

Gen-ID: 55165

UniProt: Q53EZ4