CABLES1 Antikörper (AA 530-610)

Produktnummer ABIN7213900

Der Kaninchen Polyklonal Anti-CABLES1 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, CABLES1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für CABLES1 Antikörper (AA 530-610) (ABIN7213900)

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CABLES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CABLES1 Antikörper

Bindungsspezifität: AA 530-610

Verwendungszweck: Cables1 Polyclonal Antibody

Spezifität: Cables1 Polyclonal Antibody detects endogenous levels of Cables1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Cables1 at AA range: 530-610

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CABLES1

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Andere Bezeichnung: Cables1

Hintergrund: Rabbit Anti-Cables1 Polyclonal Antibody,CABLES1, CABLES, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1, Ik3-1,CABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding different isoforms have been found for CABLES1.,CDK5 and ABL1 enzyme substrate 1

Molekulargewicht: observerd band 67kDa

Gen-ID: 91768

UniProt: Q8TDN4