Cdc14A Phosphatase (Internal Region) Antikörper

Produktnummer ABIN7225542

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Cdc14A Phosphatase in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Cdc14A Phosphatase (Internal Region) Antikörper (ABIN7225542)

Target: Cdc14A Phosphatase

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-Cdc14a phosphatase Polyclonal Antibody

Spezifität: Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Cdc14a phosphatase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Cdc14A Phosphatase

Hintergrund: CDC14A, Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog AThe protein encoded by CDC14A (cell division cycle 14A) is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of CDC14A results in several transcript variants encoding distinct isoforms.

Molekulargewicht: 66kD

Gen-ID: 8556

UniProt: Q9UNH5