CD97 beta Antikörper (Cleaved-Ser531)

Produktnummer ABIN7226090

Der Kaninchen Polyklonal anti-CD97 beta Antikörper wird verwendet zum Nachweis von CD97 beta in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA und WB.

Kurzübersicht für CD97 beta Antikörper (Cleaved-Ser531) (ABIN7226090)

Target: CD97 beta

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD97 beta Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-CD97 beta Antikörper

Bindungsspezifität: AA 480-560, Cleaved-Ser531

Verwendungszweck: Rabbit Anti-Cleaved-CD97β (S531) Polyclonal Antibody

Spezifität: Cleaved-CD97β (S531) Polyclonal Antibody detects endogenous levels of fragment of activated CD97β protein resulting from cleavage adjacent to S531.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD97beta at AA range: 480-560

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CD97 beta

Target: CD97 beta

Andere Bezeichnung: CD97beta

Hintergrund: CD97, CD97 antigen, Leukocyte antigen CD97, CD antigen CD97ADGRE5 (adhesion G protein-coupled receptor E5) encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of ADGRE5 may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

Molekulargewicht: 34kD

Gen-ID: 976

UniProt: P48960