CD158f2 (AA 130-210) Antikörper

Produktnummer ABIN7223410

Der Kaninchen Polyklonal anti-CD158f2 Antikörper wird verwendet zum Nachweis von CD158f2 in Proben von Human. Er wurde validiert für ELISA, WB und IF.

Kurzübersicht für CD158f2 (AA 130-210) Antikörper (ABIN7223410)

Target: CD158f2

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails

Bindungsspezifität: AA 130-210

Verwendungszweck: CD158f2 Polyclonal Antibody

Spezifität: CD158f2 Polyclonal Antibody detects endogenous levels of CD158f2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CD158f2 at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: CD158f2

Hintergrund: Rabbit Anti-CD158f2 Polyclonal Antibody,KIR2DL5B, CD158F, CD158F2, KIR2DL5, KIR2DLX, Killer cell immunoglobulin-like receptor 2DL5B, CD158 antigen-like family member F2, Killer cell immunoglobulin-like receptor 2DLX, CD antigen CD158f2,Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.,Killer cell immunoglobulin-like receptor 2DL5B

Molekulargewicht: observerd band 40kDa

Gen-ID: 553128

UniProt: Q8NHK3