CD101 Antikörper (Internal Region)

Produktnummer ABIN7218704

Der Kaninchen Polyklonal Anti-CD101 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CD101 in Proben von Human zu detektieren.

Kurzübersicht für CD101 Antikörper (Internal Region) (ABIN7218704)

Target: CD101

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD101 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD101 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: CD101 Polyclonal Antibody

Spezifität: CD101 Polyclonal Antibody detects endogenous levels of CD101 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CD101

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CD101

Target: CD101

Andere Bezeichnung: CD101

Hintergrund: Rabbit Anti-CD101 Polyclonal Antibody,CD101, EWI101, IGSF2, V7, Immunoglobulin superfamily member 2, IgSF2, Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101, EWI-101, CD101,CD101 (CD101 Molecule) is a Protein Coding gene. Diseases associated with CD101 include langerhans-cell histiocytosis and histiocytosis. Among its related pathways are Innate Lymphoid Cell Differentiation Pathways. Gene Ontology (GO) annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. An important paralog of this gene is PTGFRN. Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.,Immunoglobulin superfamily member 2

Molekulargewicht: observerd band 130kDa

Gen-ID: 9398

UniProt: Q93033