CNOT2 Antikörper

Produktnummer ABIN7222790

Der Kaninchen Polyklonal anti-CNOT2 Antikörper wird verwendet zum Nachweis von CNOT2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für CNOT2 Antikörper (ABIN7222790)

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CNOT2 Antikörper

Verwendungszweck: Rabbit Anti-CNOT2 Polyclonal Antibody

Spezifität: CNOT2 Polyclonal Antibody detects endogenous levels of CNOT2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CNOT2 around the non-phosphorylation site of S101

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CNOT2

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Andere Bezeichnung: CNOT2

Hintergrund: CNOT2, CDC36, NOT2, HSPC131, MSTP046, CCR4-NOT transcription complex subunit 2, CCR4-associated factor 2CNOT2 encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for CNOT2.

Molekulargewicht: 46kD

Gen-ID: 4848

UniProt: Q9NZN8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance