Cathepsin H Antikörper (AA 70-150)

Produktnummer ABIN7212456

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Cathepsin H in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Cathepsin H Antikörper (AA 70-150) (ABIN7212456)

Target: Cathepsin H (CTSH)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Cathepsin H Antikörper

Bindungsspezifität: AA 70-150

Verwendungszweck: Rabbit Anti-Cathepsin H Polyclonal Antibody

Spezifität: Cathepsin H Polyclonal Antibody detects endogenous levels of Cathepsin H protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Cathepsin H at AA range: 70-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cathepsin H

Target: Cathepsin H (CTSH)

Andere Bezeichnung: Cathepsin H

Hintergrund: CTSH, CPSB, Pro-cathepsin HThe protein encoded by CTSH is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein (cathepsin H), which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of CTSH has been correlated with malignant progression of prostate tumors. Alternate splicing of CTSH results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 40kD

Gen-ID: 1512

UniProt: P09668

Pathways: Positive Regulation of Endopeptidase Activity