Caspase 6 Subunit p11 (AA 150-230), (Cleaved-Ala194) Antikörper

Produktnummer ABIN7226778

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Caspase 6 Subunit p11 in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Caspase 6 Subunit p11 (AA 150-230), (Cleaved-Ala194) Antikörper (ABIN7226778)

Target: Caspase 6 Subunit p11

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 150-230, Cleaved-Ala194

Verwendungszweck: Rabbit Anti-Cleaved-Caspase-6 p11 (A194) Polyclonal Antibody

Spezifität: Cleaved-Caspase-6 p11 (A194) Polyclonal Antibody detects endogenous levels of Cleaved-Caspase-6 p11.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Cleaved-Caspase-6 p11 (A194) at AA range: 150-230

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Caspase 6 Subunit p11

Andere Bezeichnung: Caspase-6 p11

Hintergrund: Caspase 6, apoptosis-related cysteine peptidaseCASP6 (caspase 6) encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.

Molekulargewicht: 33kD

Gen-ID: 839

UniProt: P55212