Caspase 6 p18 (AA 120-200), (Cleaved-Asp162) Antikörper

Produktnummer ABIN7202052

Der Kaninchen Polyklonal anti-Caspase 6 p18 Antikörper wird verwendet zum Nachweis von Caspase 6 p18 in Proben von Ratte und Maus. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für Caspase 6 p18 (AA 120-200), (Cleaved-Asp162) Antikörper (ABIN7202052)

Target: Caspase 6 p18

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails

Bindungsspezifität: AA 120-200, Cleaved-Asp162

Verwendungszweck: Rabbit Anti-Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody

Spezifität: Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D162.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of mouse Caspase-6 p18 at AA range: 120-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Caspase 6 p18

Andere Bezeichnung: Caspase-6 p18

Hintergrund: CASP6, MCH2, Caspase-6, CASP-6, Apoptotic protease Mch-2CASP6 encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme.Caspase 6 is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.

Molekulargewicht: 28kD,35kD

Gen-ID: 839

UniProt: P55212