Caspase 5 p10 Antikörper (Cleaved-Ser331)

Produktnummer ABIN7212442

Der Kaninchen Polyklonal anti-Caspase 5 p10 Antikörper (ABIN7212442) detektiert spezifisch Caspase 5 p10 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Caspase 5 p10 Antikörper (Cleaved-Ser331) (ABIN7212442)

Target: Caspase 5 p10

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 5 p10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Caspase 5 p10 Antikörper

Bindungsspezifität: AA 290-370, Cleaved-Ser331

Verwendungszweck: Rabbit Anti-Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

Spezifität: Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-5 p10 protein resulting from cleavage adjacent to S331.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Caspase 5 p10

Target: Caspase 5 p10

Andere Bezeichnung: Caspase-5 p10

Hintergrund: CASP5, ICH3, Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TYCASP5 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of caspase 5 induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by caspase 5, this process requires Fas-mediated dephosphorylation of Max. The expression of CASP5 is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for CASP5.

Molekulargewicht: 10kD

Gen-ID: 838

UniProt: P51878