Caspase 2 p18 Antikörper (Cleaved-Thr325)

Produktnummer ABIN7225274

Der Kaninchen Polyklonal Anti-Caspase 2 p18 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Caspase 2 p18 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Caspase 2 p18 Antikörper (Cleaved-Thr325) (ABIN7225274)

Target: Caspase 2 p18

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 2 p18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Caspase 2 p18 Antikörper

Bindungsspezifität: AA 250-330, Cleaved-Thr325

Verwendungszweck: Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody

Spezifität: Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to T325.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Caspase-2 p18 at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Caspase 2 p18

Target: Caspase 2 p18

Andere Bezeichnung: Caspase-2 p18

Hintergrund: Rabbit Anti-Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody,CASP2, ICH1, NEDD2, Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1,CASP2 (caspase 2) encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for CASP2.,Caspase-2

Molekulargewicht: observerd band 22kDa

Gen-ID: 835

UniProt: P42575