CAPN10 Antikörper (N-Term)

Produktnummer ABIN7219246

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CAPN10 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CAPN10 Antikörper (N-Term) (ABIN7219246)

Target: CAPN10 (Calpain 10 (CAPN10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAPN10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CAPN10 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Calpain 10 Polyclonal Antibody

Spezifität: Calpain 10 Polyclonal Antibody detects endogenous levels of Calpain 10 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Calpain 10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CAPN10

Target: CAPN10 (Calpain 10 (CAPN10))

Andere Bezeichnung: Calpain 10

Hintergrund: Rabbit Anti-Calpain 10 Polyclonal Antibody,CAPN10, KIAA1845, Calpain-10, Calcium-activated neutral proteinase 10, CANP 10,Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. CAPN10 encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. CAPN10 is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.,Calpain-10

Molekulargewicht: observerd band 75kDa

Gen-ID: 11132

UniProt: Q9HC96

Pathways: Positive Regulation of Peptide Hormone Secretion