Calcitonin Receptor Antikörper (AA 410-490)
Kurzübersicht für Calcitonin Receptor Antikörper (AA 410-490) (ABIN7227578)
Target
Alle Calcitonin Receptor (CALCR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 410-490
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Verwendungszweck
- Rabbit Anti-CALCR Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of CALCR protein
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human CALCR protein at AA range: 410-490
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- Calcitonin Receptor (CALCR)
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Andere Bezeichnung
- CALCR
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Hintergrund
- Calcitonin receptor, CT-RCALCR encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in CALCR have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
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Molekulargewicht
- 53kD
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Gen-ID
- 799
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UniProt
- P30988
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Pathways
- cAMP Metabolic Process
Target
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