Der Kaninchen Polyklonal anti-Calcitonin Antikörper wird verwendet zum Nachweis von Calcitonin in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.
Calca
Reaktivität: Maus
WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300,WB 1:500-2000,ELISA 1:10000-20000,IF 1:50-200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
Calcitonin (Calca)
Andere Bezeichnung
Calcitonin
Hintergrund
CalcitoninCALCA encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for CALCA. CALCA (Calcitonin Related Polypeptide Alpha) is a Protein Coding gene. Diseases associated with CALCA include Reflex Sympathetic Dystrophy and Complex Regional Pain Syndrome. Among its related pathways are G alpha(s) signalling events and Signaling by GPCR.