Cadherin 7 Antikörper (AA 620-700)

Produktnummer ABIN7213912

Der Kaninchen Polyklonal anti-Cadherin 7 Antikörper wird verwendet zum Nachweis von Cadherin 7 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für Cadherin 7 Antikörper (AA 620-700) (ABIN7213912)

Target: Cadherin 7 (CDH7)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Cadherin 7 Antikörper

Bindungsspezifität: AA 620-700

Verwendungszweck: Rabbit Anti-Cadherin-7 Polyclonal Antibody

Spezifität: Cadherin-7 Polyclonal Antibody detects endogenous levels of Cadherin-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Cadherin-7 at AA range: 620-700

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cadherin 7

Target: Cadherin 7 (CDH7)

Andere Bezeichnung: Cadherin-7

Hintergrund: CDH7, CDH7L1, Cadherin-7CDH7 encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in CDH7 may be associated with bipolar disease in human patients. CDH7 is present in a gene cluster on chromosome 18.

Molekulargewicht: 87kD

Gen-ID: 1005

UniProt: Q9ULB5

Pathways: Cell-Cell Junction Organization