CDH23 Antikörper (AA 30-110)

Produktnummer ABIN7224214

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CDH23 in ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CDH23 Antikörper (AA 30-110) (ABIN7224214)

Target: CDH23 (Cadherin 23 (CDH23))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDH23 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-CDH23 Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: Rabbit Anti-Cadherin-23 Polyclonal Antibody

Spezifität: Cadherin-23 Polyclonal Antibody detects endogenous levels of Cadherin-23 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Cadherin-23 at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CDH23

Target: CDH23 (Cadherin 23 (CDH23))

Andere Bezeichnung: Cadherin-23

Hintergrund: CDH23, KIAA1774, KIAA1812, Cadherin-23, OtocadherinCDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of CDH23 may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

Gen-ID: 64072

UniProt: Q9H251

Pathways: Sensory Perception of Sound