BTBD6 Antikörper (AA 60-140)

Produktnummer ABIN7225764

Der Kaninchen Polyklonal Anti-BTBD6 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, BTBD6 in Proben von Human und Maus zu detektieren.

Kurzübersicht für BTBD6 Antikörper (AA 60-140) (ABIN7225764)

Target: BTBD6 (BTB (POZ) Domain Containing 6 (BTBD6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BTBD6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BTBD6 Antikörper

Bindungsspezifität: AA 60-140

Verwendungszweck: BTBD6 Polyclonal Antibody

Spezifität: BTBD6 Polyclonal Antibody detects endogenous levels of BTBD6 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human BTBD6 at AA range: 60-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu BTBD6

Target: BTBD6 (BTB (POZ) Domain Containing 6 (BTBD6))

Andere Bezeichnung: BTBD6

Hintergrund: Rabbit Anti-BTBD6 Polyclonal Antibody,BTBD6, BDPL, BTB/POZ domain-containing protein 6, Lens BTB domain protein,BTBD6 (BTB/POZ domain-containing protein 6), also known as BDPL or lens BTB domain protein, is a 410 amino acid protein that contains one BTB/POZ domain and is specifically expressed in the lens. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD6 may play a role in transcription regulation in the lens.,BTB

Molekulargewicht: observerd band 45kDa

Gen-ID: 90135

UniProt: Q96KE9