BCAS3 Antikörper (AA 660-740)

Produktnummer ABIN7223322

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch BCAS3 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für BCAS3 Antikörper (AA 660-740) (ABIN7223322)

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCAS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-BCAS3 Antikörper

Bindungsspezifität: AA 660-740

Verwendungszweck: BCAS3 Polyclonal Antibody

Spezifität: BCAS3 Polyclonal Antibody detects endogenous levels of BCAS3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human BCAS3 at AA range: 660-740

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu BCAS3

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Andere Bezeichnung: BCAS3

Hintergrund: Rabbit Anti-BCAS3 Polyclonal Antibody,BCAS3, Breast carcinoma-amplified sequence 3, GAOB1,Rudhira/BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98 % identical and the gene maps to a breakpoint of hematological neoplasms on chromosome 17q23. BCAS3 is also expressed in vascular development in embryoid bodies in vitro and was originally identified as a gene over-expressed in breast cancers. It is reported to be a target of metastasis associated protein-1 (MTA-1). Further BCAS3 expression is also upregulated in grade III and IV glioblastomas where it is misexpressed in the tumor cells.,Breast carcinoma-amplified sequence 3

Gen-ID: 54828

UniProt: Q9H6U6