BRSK1 Antikörper (AA 330-410)

Produktnummer ABIN7213854

Dieser Anti-BRSK1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von BRSK1 in WB, ELISA und IF. Geeignet für Human und Maus.

Kurzübersicht für BRSK1 Antikörper (AA 330-410) (ABIN7213854)

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRSK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-BRSK1 Antikörper

Bindungsspezifität: AA 330-410

Verwendungszweck: BRSK1 Polyclonal Antibody

Spezifität: BRSK1 Polyclonal Antibody detects endogenous levels of BRSK1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human BRSK1 at AA range: 330-410

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu BRSK1

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Andere Bezeichnung: BRSK1

Hintergrund: Rabbit Anti-BRSK1 Polyclonal Antibody,BRSK1, KIAA1811, SAD1, SADB, Serine/threonine-protein kinase BRSK1, Brain-selective kinase 1, Brain-specific serine/threonine-protein kinase 1, BR serine/threonine-protein kinase 1, Serine/threonine-protein kinase SAD-B, Synapses of Amphids,The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. BRSK1 (BR serine/threonine-protein kinase 1), also known as SAD1, is a 794 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one UBA domain and one protein kinase domain. Expressed in a variety of tissues with highest expression in testis and brain, BRSK1 uses magensium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins, including Wee 1 and Cdc25B. Via its kinase activity toward proteins that are involved in microtubule assembly, BRSK1 plays an essential role in neuronal polarization and may be involved in regulating cell cycle arrest in response to DNA damage, Two isoforms of BRSK1 exist due to alternative splicing events.,serine threonine-protein kinase BRSK1

Molekulargewicht: observerd band 87kDa

Gen-ID: 84446

UniProt: Q8TDC3