BMP8A Antikörper (AA 230-310)

Produktnummer ABIN7213826

Der Kaninchen Polyklonal anti-BMP8A Antikörper wird verwendet zum Nachweis von BMP8A in Proben von Human und Maus. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für BMP8A Antikörper (AA 230-310) (ABIN7213826)

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-BMP8A Antikörper

Bindungsspezifität: AA 230-310

Verwendungszweck: Rabbit Anti-BMP-8A Polyclonal Antibody

Spezifität: BMP-8A Polyclonal Antibody detects endogenous levels of BMP-8A protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human BMP-8A at AA range: 230-310

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu BMP8A

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Andere Bezeichnung: BMP-8A

Hintergrund: BMP8A, Bone morphogenetic protein 8A, BMP-8ABMP8A encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. BMP8A may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.

Molekulargewicht: 45-55kD

Gen-ID: 353500

UniProt: Q7Z5Y6

Pathways: Negative Regulation of Hormone Secretion