Atrophin 1 Antikörper (AA 50-130)

Produktnummer ABIN7213736

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Atrophin 1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Atrophin 1 Antikörper (AA 50-130) (ABIN7213736)

Target: Atrophin 1 (ATN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Atrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Atrophin 1 Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Rabbit Anti-Atrophin-1 Polyclonal Antibody

Spezifität: Atrophin-1 Polyclonal Antibody detects endogenous levels of Atrophin-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Atrophin-1 at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Atrophin 1

Target: Atrophin 1 (ATN1)

Andere Bezeichnung: Atrophin-1

Hintergrund: ATN1, D12S755E, DRPLA, Atrophin-1, Dentatorubral-pallidoluysian atrophy proteinDentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Molekulargewicht: 130kD

Gen-ID: 1822

UniProt: P54259