AGBL2 Antikörper (AA 700-780)

Produktnummer ABIN7214030

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AGBL2 in ELISA, WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für AGBL2 Antikörper (AA 700-780) (ABIN7214030)

Target: AGBL2 (ATP/GTP Binding Protein-Like 2 (AGBL2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGBL2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-AGBL2 Antikörper

Bindungsspezifität: AA 700-780

Verwendungszweck: Rabbit Anti-CCP2 Polyclonal Antibody

Spezifität: CCP2 Polyclonal Antibody detects endogenous levels of CCP2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human CCP2 at AA range: 700-780

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu AGBL2

Target: AGBL2 (ATP/GTP Binding Protein-Like 2 (AGBL2))

Andere Bezeichnung: CCP2

Hintergrund: AGBL2, CCP2, Cytosolic carboxypeptidase 2, ATP/GTP-binding protein-like 2The peptidase M14 family of carboxypeptidases (CPs) are involved in various functions throughout the body which include digestion of food and biosynthesis of peptides that function in intercellular signaling. CCP2 (cytosolic carboxypeptidase 2), also known as AGBL2 (ATP/GTP binding protein-like 2), is a 902 amino acid cytoplasmic protein belonging to the peptidase M14 family. CCP2 is considered a metallocarboxypeptidase that may play a role in the processing of tubulin. CCP2 binds one zinc ion per subunit as a cofactor and exists as three alternatively spliced isoforms. The gene encoding CCP2 is located on human chromosome 11p11.2. Chromosome 11 houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Molekulargewicht: 104kD

Gen-ID: 79841

UniProt: Q5U5Z8