Ataxin-7L1 (AA 410-490) Antikörper

Produktnummer ABIN7220502

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Ataxin-7L1 in ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Ataxin-7L1 (AA 410-490) Antikörper (ABIN7220502)

Target: Ataxin-7L1

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails

Bindungsspezifität: AA 410-490

Verwendungszweck: Rabbit Anti-Ataxin-7L1 Polyclonal Antibody

Spezifität: Ataxin-7L1 Polyclonal Antibody detects endogenous levels of Ataxin-7L1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Ataxin-7L1 at AA range: 410-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Ataxin-7L1

Hintergrund: ATXN7L1, ATXN7L4, KIAA1218, Ataxin-7-like protein 1, Ataxin-7-like protein 4ATXN7L3 (ataxin-7-like protein 3) is a 347 amino acid transcription protein that belongs to the SGF11 family. ATXN7L3 localizes to nucleus and contains one SCA7 domain and one SGF11-type zinc finger. The SGF11-type zinc finger of ATXN7L3 mediates the interaction with USP22 and ENY2. ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, which is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 contributes to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The ATXN7L3 gene exists as two alternatively spliced isoforms, is conserved in chimpanzee, dog, cow, rat, zebrafish, fruit fly and mosquito, and maps to human chromosome 17q21.1.

Gen-ID: 222255

UniProt: Q9ULK2