Ataxin-7L1 (AA 410-490) Antikörper

Produktnummer ABIN7220502

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch not_set in ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Ataxin-7L1 (AA 410-490) Antikörper (ABIN7220502)

Target: Ataxin-7L1

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: AA 410-490

Verwendungszweck: Ataxin-7L1 Polyclonal Antibody

Spezifität: Ataxin-7L1 Polyclonal Antibody detects endogenous levels of Ataxin-7L1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Ataxin-7L1 at AA range: 410-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: Ataxin-7L1

Hintergrund: Rabbit Anti-Ataxin-7L1 Polyclonal Antibody,ATXN7L1, ATXN7L4, KIAA1218, Ataxin-7-like protein 1, Ataxin-7-like protein 4,ATXN7L3 (ataxin-7-like protein 3) is a 347 amino acid transcription protein that belongs to the SGF11 family. ATXN7L3 localizes to nucleus and contains one SCA7 domain and one SGF11-type zinc finger. The SGF11-type zinc finger of ATXN7L3 mediates the interaction with USP22 and ENY2. ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, which is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 contributes to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The ATXN7L3 gene exists as two alternatively spliced isoforms, is conserved in chimpanzee, dog, cow, rat, zebrafish, fruit fly and mosquito, and maps to human chromosome 17q21.1.,Ataxin-7-like protein 1

Gen-ID: 222255

UniProt: Q9ULK2