AVPR1B Antikörper (AA 250-330)

Produktnummer ABIN7213742

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AVPR1B in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für AVPR1B Antikörper (AA 250-330) (ABIN7213742)

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AVPR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-AVPR1B Antikörper

Bindungsspezifität: AA 250-330

Verwendungszweck: Rabbit Anti-AVP Receptor V3 Polyclonal Antibody

Spezifität: AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human AVP Receptor V3 at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Andere Bezeichnung: AVP Receptor V3

Hintergrund: AVPR1B, AVPR3, VPR3, Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptorThe protein (arginine vasopressin receptor 1B) encoded by AVPR1B acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of AVPR1B has been reported but its function is not known.

Molekulargewicht: 47kD

Gen-ID: 553

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones