AVEN Antikörper (AA 270-350)

Produktnummer ABIN7213740

Der Kaninchen Polyklonal Anti-AVEN Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, AVEN in Proben von Human und Affe zu detektieren.

Kurzübersicht für AVEN Antikörper (AA 270-350) (ABIN7213740)

Target: AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AVEN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AVEN Antikörper

Bindungsspezifität: AA 270-350

Verwendungszweck: Aven Polyclonal Antibody

Spezifität: Aven Polyclonal Antibody detects endogenous levels of Aven protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Aven at AA range: 270-350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu AVEN

Target: AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))

Andere Bezeichnung: Aven

Hintergrund: Rabbit Anti-Aven Polyclonal Antibody,AVEN, Cell death regulator Aven,AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.,Cell death regulator Aven

Gen-ID: 57099

UniProt: Q9NQS1