ANKRD30A Antikörper (AA 1010-1090)

Produktnummer ABIN7213582

Der Kaninchen Polyklonal anti-ANKRD30A Antikörper wird verwendet zum Nachweis von ANKRD30A in Proben von Human. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für ANKRD30A Antikörper (AA 1010-1090) (ABIN7213582)

Target: ANKRD30A (Ankyrin Repeat Domain 30A (ANKRD30A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD30A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ANKRD30A Antikörper

Bindungsspezifität: AA 1010-1090

Verwendungszweck: Rabbit Anti-ANKRD30A Polyclonal Antibody

Spezifität: ANKRD30A Polyclonal Antibody detects endogenous levels of ANKRD30A protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human ANKRD30A at AA range: 1010-1090

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ANKRD30A

Target: ANKRD30A (Ankyrin Repeat Domain 30A (ANKRD30A))

Andere Bezeichnung: ANKRD30A

Hintergrund: ANKRD30A, Ankyrin repeat domain-containing protein 30A, Serologically defined breast cancer antigen NY-BR-1Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD30A (ankyrin repeat domain 30A), also known as serologically defined breast cancer antigen NY-BR-1, is a 1,397 amino acid coiled-coil protein. Containing six ANK repeats and thirty-seven exons, ANKRD30A is a distant homolog of the POTE family. Initiated by either Dnmt1 or Met-57, ANKRD30A is highly expressed in breast and testis, and faintly in placenta. Present in 80 % of breast cancers, but not in other types of tumors, ANKRD30A is a differentiation antigen and a potential target for antibody-based therapies in breast cancers.

Molekulargewicht: 153kD

Gen-ID: 91074

UniProt: Q9BXX3