DCAF6 Antikörper (AA 245-350) (Cy3)

Produktnummer ABIN715784

Der Kaninchen Polyklonal Anti-DCAF6-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, DCAF6 in Proben von Human zu detektieren.

Kurzübersicht für DCAF6 Antikörper (AA 245-350) (Cy3) (ABIN715784)

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCAF6 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DCAF6 Antikörper (Cy3)

Bindungsspezifität: AA 245-350

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NRIP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DCAF6

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Andere Bezeichnung: NRIP

Hintergrund:

Synonyms: Androgen receptor complex associated protein, ARCAP, IQ mot and WD repeats 1, IQWD1v MSTP055, Nuclear receptor interaction protein, RP4 745I14.1, DCAF6_HUMAN.

Background: WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

Gen-ID: 8204